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The loss of RNA N(6)-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8(+) T cell dysfunction and tumor growth. 2021
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance 2021
N(6)-methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA. 2021
METTL3-dependent m(6)A modification programs T follicular helper cell differentiation. 2021
MYC promotes cancer progression by modulating m(6) A modifications to suppress target gene translation. 2021
Germline variants of DNA repair genes in early onset mantle cell lymphoma. 2021
Compositional Variability and Mutation Spectra of Monophyletic SARS-CoV-2 Clades. 2021
RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks. 2021
The UVSSA complex alleviates MYC-driven transcription stress. 2021
Evidence for CAT gene being functionally involved in the susceptibility of COVID-19. 2021
Increased chromosomal instability characterizes metastatic renal cell carcinoma. 2021
Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms. 2021
Computing the Role of Alternative Splicing in Cancer. 2021
Comprehensive Analysis of Expression Regulation for RNA m6A Regulators With Clinical Significance in Human Cancers. 2021
Mutant SF3B1 promotes AKT and NF-kB driven mammary tumorigenesis. 2021
Genomic Analysis Revealed a Convergent Evolution of LINE-1 in Coat Color: A Case Study in Water Buffaloes (Bubalus bubalis). 2021
Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse. 2021
Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution. 2021
A host-based two-gene model for the identification of bacterial infection in general clinical settings. 2021
Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis. 2021
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